Should you want 3.5" of substrate depth - 48 x 18 x 3.5 divided by 28 = 108
lbs of Flourite.
The 2" SeaChem states is a general term to let you know how much coverage
you will get out of one bag in a 10 gallon aquarium (IMHO). On the other
hand though, by figuring out the total square inches of your tank bottom
(864) and dividing that by 31 (SeaChem's recommendation below) you come up
with 27.87. Multiplying 27.87 by 2.2 (pounds in one kilo) you get 61.3 lbs.,
which is very close to the figure above for amount of Flourite needed for 2"
of coverage. Perhaps Dr. Morin from SeaChem can confirm or dispel these
suspicions.